Introducing Spine Agent 2.4: Autonomous multi-physics routing for surgical biomechanics.Explore live console
OurMission
Pioneering Computational Surgical Intelligence

Biomechanical guesswork shouldn’t stand between spine surgeons and the care they deliver.SpineTwin exists to help healthcare teams eliminate mechanical failure with computational certainty.

We bridge the gap between surgical intuition and computational mechanics—replacing manual guesswork with patient-specific AI and finite element simulations to protect every patient from implant failure.

SpineTwin in
numbers

Empirical clinical validation and biomechanical scale across North American research hospitals.

22%+

Higher sagittal alignment restoration accuracy compared to traditional manual templating

50%+

Lower computational solve time for patient-specific nonlinear finite element meshing

60%+

Reduction in post-operative junctional mechanical risk and revision probability

500k+

Biomechanical stress iterations simulated across validated anatomical spine models

Founding Team & Science

Built by Leaders in Biomechanics. Medical imaging & AI.

Combining world-class academic pedigree across Stanford, Georgia Tech, and McGill with practicing orthopedic spine surgeons.

Founding Scientisth-index 19

Farshid Ghezelbash, PhD

Co-Founder · Biomechanics & AI

Polytechnique Montréal · McGill · Georgia Tech

Pioneered computational trunk musculoskeletal modeling, personalized spinal finite element simulations, and multi-physics solver integrations.

h-index 19 · 40+ Peer-Reviewed Publications
Founding Engineerh-index 14

Amir Hossein Eskandari, PhD

Co-Founder · Medical Imaging & Biomechanics

UBC Radiology · IRSST · Torus Biomedical

Expert in deep learning X-ray segmentation, statistical shape modeling, and robot-assisted cortical bone breach prevention algorithms.

h-index 14 · STP Pedicle Screw Trajectory Lead
AI ArchitectureFirst Author WCB 2026

Dianze Liu

Co-Founder · Machine Learning & Software

Georgia Tech Design Intelligence Lab · WCB 2026

Specialist in autonomous agent architectures, zero-shot biomechanical parameter sweeps, and web-scale in-browser kinematic solvers.

First Author WCB 2026 · LoRA Initializations

Clinical Advisory Board

Guiding surgical sanity rules and cadaver verification

Michael P. Kelly, MD

Spine Surgeon · Stanford University School of Medicine

Complex Adult Spinal Deformity & Surgical Kinematics

Jeff Hills, MD

Spine Surgeon · UT Health San Antonio

Clinical Surgical Planning & Construct Failure Prevention

CLINICAL & ACADEMIC PEDIGREE

Validated Across Leading Research Institutions

Our models and simulation algorithms are built upon decades of peer-reviewed research and validated biomechanical datasets.

Montréal, QC

Polytechnique Montréal

Trunk Musculoskeletal Biomechanics Lab

Decades of in-vitro cadaveric testing, non-linear disc calibrations, and 552-muscle static trunk models.

Montréal, QC

McGill University

Biomedical R&D & Sensory Technology

Pre-clinical implant validation, sensory kinematics, and bone-screw interface mechanics.

Vancouver, BC

UBC Radiology

Spine Biomechanics & Medical Imaging

2D-to-3D deep learning landmark detection and automated radiological sagittal alignment verification.

Stanford, CA

Stanford Medicine

Surgical Advisory & Clinical Validation

Clinical alignment targets, SRS-Schwab grade 0 restoration protocols, and post-op mechanical stability criteria.

Atlanta, GA

Georgia Tech

Design Intelligence Lab & ML LoRA Research

Multi-agent autonomous solver orchestration and zero-shot computational code synthesis.

Montréal, QC

IRSST

Occupational Biomechanics & Spine Loading

Ergonomic lifting dynamics, NIOSH lifting equation boundary modeling, and disc compressive stress profiles.

Clinical Pedigree & Research Validation

Backed by Clinical Research. Academic excellence across leading centers.

Stanford Medicine
Stanford, CA

Stanford Medicine

Surgical Advisory & Clinical Validation

Georgia Tech
Atlanta, GA

Georgia Tech

Design Intelligence Lab & ML LoRA Research

UT Health San Antonio
San Antonio, TX

UT Health San Antonio

Spine Surgery Advisory Board

Polytechnique Montréal
Montréal, QC

Polytechnique Montréal

Trunk Musculoskeletal Biomechanics Lab

McGill University
Montréal, QC

McGill University

Biomedical R&D & Sensory Technology

UBC Radiology
Vancouver, BC

UBC Radiology

Spine Biomechanics & Medical Imaging

IRSST
Canada

IRSST

Occupational Biomechanics & Spine Loading

Torus Biomedical
Canada

Torus Biomedical

Robotic Spine Drilling & Instrumentation

Clinical Calendar

Schedule a Clinical Review. Direct technical demo.

Book directly with the founding scientists or submit your institution's specific surgical simulation requirements.

Select a Team Member to Book Directly:

Farshid Ghezelbash, PhD

Biomechanics & Modeling Review

Discuss finite element mesh morphing, cadaver kinematics validation, and musculoskeletal model calibrations.

Amir Hossein Eskandari, PhD

Clinical Imaging & STP Screws

Evaluate machine learning landmark detection on your center's X-rays and cortical bone breach safety algorithms.

Dianze Liu

AI Architecture & Foundry Integration

Explore agent zero-shot parameter sweeps, custom Python solver automation, and Medtronic POC workflows.

General Clinical Inquiries

Custom pilot datasets & device integrations

HIPAA & SOC 2 Type II Ready24h Response SLA